Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_02_BT_ATM_minus_versus_ATM_plus.phenotype_BT_ATM_minus_versus_ATM_plus.cls #BT_ATM_minus_versus_ATM_plus.phenotype_BT_ATM_minus_versus_ATM_plus.cls #BT_ATM_minus_versus_ATM_plus_repos |
| Phenotype | phenotype_BT_ATM_minus_versus_ATM_plus.cls#BT_ATM_minus_versus_ATM_plus_repos |
| Upregulated in class | BT_ATM_minus |
| GeneSet | NCI_ALPHA-SYNUCLEIN SIGNALING |
| Enrichment Score (ES) | 0.48011062 |
| Normalized Enrichment Score (NES) | 1.5501089 |
| Nominal p-value | 0.03768844 |
| FDR q-value | 0.56405264 |
| FWER p-Value | 1.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | PTK2B | 1434653_at 1442437_at 1442927_at | 16 | 3.364 | 0.1537 | Yes | ||
| 2 | LCK | 1425396_a_at 1439145_at 1439146_s_at 1457917_at | 50 | 2.528 | 0.2682 | Yes | ||
| 3 | FYN | 1417558_at 1441647_at 1448765_at | 216 | 1.850 | 0.3456 | Yes | ||
| 4 | SYK | 1418261_at 1418262_at 1425797_a_at 1457239_at | 557 | 1.383 | 0.3935 | Yes | ||
| 5 | PARK2 | 1420755_a_at 1426135_a_at 1449975_a_at | 1445 | 0.980 | 0.3980 | Yes | ||
| 6 | STUB1 | 1416580_a_at 1429069_at 1434412_x_at | 1481 | 0.974 | 0.4412 | Yes | ||
| 7 | HCK | 1446553_at 1449455_at | 1585 | 0.951 | 0.4801 | Yes | ||
| 8 | TH | 1420546_at | 3584 | 0.552 | 0.4142 | No | ||
| 9 | PLD2 | 1417237_at 1457252_x_at | 4991 | 0.392 | 0.3680 | No | ||
| 10 | CSNK2A1 | 1419034_at 1419035_s_at 1419036_at 1419037_at 1419038_a_at 1453427_at | 6948 | 0.227 | 0.2891 | No | ||
| 11 | SLC6A3 | 1417415_at | 7144 | 0.213 | 0.2900 | No | ||
| 12 | PARK7 | 1416526_a_at 1456194_a_at | 8660 | 0.110 | 0.2258 | No | ||
| 13 | YES1 | 1418470_at 1449090_a_at 1456843_at 1458878_at | 10051 | 0.022 | 0.1634 | No | ||
| 14 | FGR | 1419526_at 1442804_at | 10416 | -0.000 | 0.1468 | No | ||
| 15 | MAPK1 | 1419568_at 1426585_s_at 1442876_at 1453104_at | 11428 | -0.064 | 0.1036 | No | ||
| 16 | SRC | 1423240_at 1450918_s_at | 12489 | -0.129 | 0.0611 | No | ||
| 17 | BLK | 1422775_at | 12579 | -0.135 | 0.0632 | No | ||
| 18 | BAD | 1416582_a_at 1416583_at | 13788 | -0.213 | 0.0179 | No | ||
| 19 | FKBP1A | 1416036_at 1438795_x_at 1438958_x_at 1448184_at 1456196_x_at | 13886 | -0.221 | 0.0236 | No | ||
| 20 | PLCB2 | 1452481_at | 14116 | -0.236 | 0.0240 | No | ||
| 21 | MAOB | 1434354_at | 14988 | -0.299 | -0.0021 | No | ||
| 22 | SNCA | 1418493_a_at 1431022_at 1436853_a_at 1446391_at | 15045 | -0.303 | 0.0093 | No | ||
| 23 | PPP2R5D | 1450560_a_at | 15359 | -0.326 | 0.0100 | No | ||
| 24 | TOR1A | 1426515_a_at | 15884 | -0.367 | 0.0029 | No | ||
| 25 | KLK6 | 1448982_at | 17201 | -0.489 | -0.0348 | No | ||
| 26 | UBE2L3 | 1417907_at 1417908_s_at 1448879_at 1448880_at | 18651 | -0.675 | -0.0699 | No | ||
| 27 | MAPK3 | 1427060_at | 18852 | -0.706 | -0.0467 | No | ||
| 28 | UCHL1 | 1448260_at | 19048 | -0.737 | -0.0217 | No | ||
| 29 | PLD1 | 1425739_at 1437112_at 1437113_s_at | 19967 | -0.925 | -0.0212 | No | ||
| 30 | GRK5 | 1446361_at 1446998_at 1449514_at | 20463 | -1.039 | 0.0039 | No | ||
| 31 | PRKCD | 1422847_a_at 1442256_at | 21204 | -1.377 | 0.0333 | No |
